In Christian County, two vehicles collided Saturday night.
Illinois State Police said, Debra Patterson, 49, was driving just west of Inlaid on Route 104 when she crossed the center lane and hit a vehicle head-on.
Patterson died at the scene.
Two people in the other vehicle were transported to Taylorville Memorial Hospital with non-life threatening injuries.
The crash remains under investigation. Police said, alcohol does not appear to be a factor in the crash.