Health officials say Israeli strikes and gunfire have killed at least 59 people across Gaza. This comes as international pressure grows for a ceasefire, but Israel's leader remains defiant. Among the dead are nine from the same family in a refugee camp. The attacks occurred after Israeli Prime Minister Benjamin Netanyahu told the U.N. General Assembly that Israel "must finish the job" against Hamas. Countries are urging the U.S. to press Israel for a ceasefire. Meanwhile, hospitals in Gaza are on the brink of collapse, with shortages of medicine, equipment and food.

U.S. Secretary of State Marco Rubio has arrived in Israel as it intensifies attacks on northern Gaza. Rubio's two-day visit aims to show support for Israel which faces isolation before a U.N. debate on a Palestinian state. Israeli Prime Minister Benjamin Netanyahu opposes this recognition. U.S. President Donald Trump is upset with Netanyahu for an Israeli strike in Doha without U.S. notification. Rubio and Trump met with Qatar’s prime minister on Friday to discuss the situation. The attack has hindered ceasefire efforts and hostage releases before the U.N. General Assembly session. Rubio arrived in Israel on Sunday.

Israel has intensified airstrikes in Gaza City, killing at least 32 people, including 12 children, according to medical staff. The strikes are part of an offensive to take over the city, which Israel claims is Hamas' last stronghold. Despite urging residents to evacuate, hundreds of thousands remain, facing famine and dire conditions. The United Nations reports over 100,000 people have left since mid-August, but many are stuck due to high costs and limited and overcrowded areas to go to. A U.N. initiative to bring temporary shelters into Gaza said more than 86,000 tents and other supplies were still awaiting clearance to enter Gaza as of last week.

Israel’s military warned Gaza City residents to evacuate ahead of its plans to take control of what it portrays as Hamas’ last remaining stronghold and where hundreds of thousands of people remain under conditions of famine. The warning came on Tuesday ahead of an Israeli strike targeting Hamas’ leaders in Qatar, where negotiations over ending the war in Gaza appeared at a standstill. The warnings directed at Gaza City are the first calling for a full evacuation. Associated Press reporters saw lines of cars and trucks leaving on Tuesday, more than previous days. Children and adults sat atop piles of blankets, furniture, and clothing stacked on trucks and wagons.

Israel has struck and destroyed another high-rise building in Gaza City after warning residents to evacuate as part of an offensive aimed at taking over the largest Palestinian city. The military said it was targeting Hamas observation posts and bombs placed around the 12-story office building. U.S. President Donald Trump said that he was giving his “last warning” to Hamas regarding a possible ceasefire as Arab officials described a new U.S. proposal. In Jerusalem, meanwhile, two Palestinian gunmen opened fire at a bus station, killing six people in the worst such attack on Israelis in nearly a year.

The Israeli army has issued evacuation orders and targeted high-rise buildings in famine-stricken Gaza City. The army spokesperson on Saturday called on Palestinians to move to the territory’s south as it escalates operations ahead of new offensive to seize the city of nearly 1 million. Aid groups warn that a large-scale evacuation would exacerbate the humanitarian crisis in Gaza City, which the world’s leading hunger watchdog says is suffering from famine. Most families have already been displaced several times over the nearly two-year-long Israel-Hamas war and say they have nowhere left to go. The army also issued evacuation orders for two high-rises in Gaza City that it alleged hosted Hamas infrastructure, without providing evidence.

Pope Leo XIV and his top diplomats have told Israel’s president that a two-state solution is the “only way out of the war,” in Gaza. During a meeting Thursday, the Vatican called for a permanent ceasefire in Gaza, the release of all hostages and entry of humanitarian aid to famine-stricken Palestinians there. The Vatican issued an unusually detailed statement following Leo’s meeting with Israeli President Isaac Herzog, who met with the Vatican secretary of state and foreign minister. The audience marked the first by history’s first American pope with the Israeli head of state. Leo spoke by telephone with Prime Minister Benjamin Netanyahu in July after an Israeli shell hit the only Catholic church in Gaza, killing three people and wounding the parish priest.