Secretary of State Marco Rubio and Vice President JD Vance are both seen as the Republican Party’s strongest potential candidates in the next presidential election, but the Iran war could prove to be a political millstone for them. Rubio’s full-throated support for the war could come back to haunt him depending on how the war turns out. Vance risks accusations of disloyalty if he were to stray too far from President Donald Trump's messaging, but an appearance of support for the war could be seen as an about-face given his longtime skepticism of foreign military interventions. The White House says the Republican president has full confidence in Vance and Rubio.